Evidence-based professional reference pages authored by our clinical team for the use of medical professionals. An acute exacerbation is more commonly known birli a 'flare-up'. An acute exacerbation of chronic obstructive pulmonary disease (COPD) is a sudden worsening of COPD symptoms compared with the usual severity of symptoms. Steroid enjeksiyonları: https://www.ird.gov.lk/en/Lists/QuickFeedback/DispForm.aspx?ID=262745